Chadwick Prodromos, M.D.

Rush Medical College Surgical Sciences Research Award
Berkheiser Research Award of the Institute of Medicine of Chicago

Editor in Chief: The ANTERIOR CRUCIATE LIGAMENT: Reconstruction and Basic Science
Publisher: Elsevier:

First Edition: October 2007,
Associate Editors: Freddie Fu, Steve Howell, Don Shelbourne, Lonnie Paulos,
Charlie Brown, Tassos Georgulies, Alberto Gobbi, Don Johnson
Second Edition: July 2017
Associate Editors: Andrews, Brown, Fu, Georgoulis, Gobbi, Noyes, Shelbourne

 

Contributor: PRACTICAL ORTHOPAEDIC SPORTS MEDICINE AND ARTHROSCOPY
Publisher: Lippincott Williams and Wilkins: December 2006
Editor: Donald Johnson
Chapters
1) Posterior Hamstring Harvest Technique
2) The Team Physician

 

Contributor: THE SHOULDER
Publisher: Churchill Livingstone 1988
Editors: Carter Rowe
Chapter: Shoulder Injuries in Sports

 

Chadwick Prodromos, Ruby Del Villar, Andrew Striegel, Gerard Pena, Rohan Dixit, and Amy Xu. Stem Cell and Exosome Treatment for Organ Health and Longevity: A Systematic Review. International Journal of Molecular Sciences, 2026 October; 27(20): 9174.

Chadwick Prodromos, Ruby Del Villar, Gerard Pena, Andrew Striegel, Rohan Dixit, and Kenneth Candido. First Report of Successful Exosome and Stem Cell Treatment of Migraine Headache: A Report of Two Cases. Posted on ResearchGate, August 2026.

Chadwick Prodromos, Ruby Del Villar, Gerard Pena, Andrew Striegel, Rohan Dixit, and Angelina Bottalico. The Secretome and Exosomes from Cultured Mesenchymal Stem Cells Improves Quality of Life in Patients with Parkinson’s Disease. Posted on ResearchGate, July 2026.

Chadwick Prodromos, Ruby Del Villar, Drew Gura, and Kenneth Candido. Exosome-Rich Mesenchymal Stem Cell Secretome Improves Symptoms From Parkinson’s Disease: A Case Series. Pain Medicine Case Reports, 2026 May; 10(3): 259-266.
Chadwick Prodromos, Andrew Striegel, Drew Gura, Lukas Henjum, Alaa Abd-Elsayed, and Kenneth Candido. Exosome-Rich Mesenchymal Stem Cell Secretome Reverses Presbycusis: A Case Report. Posted on ResearchGate, May 2026.

Chadwick Prodromos, Drew Gura, Michelle Li, Lukas Henjum, Alaa Abd-Elsayed, and Kenneth Candido. Exosome-Rich Mesenchymal Stem Cell Secretome Improves Trigeminal Neuralgia Symptoms: A Report of Two Cases. Posted on ResearchGate, May 2026.

Chadwick Prodromos, Ruby Del Villar, Andrew Striegel, Gerard Pena, and Rohan Dixit. The Molecular Basis of Partial Reversal or Significant Slowing of ALS, Parkinson’s Disease, and Lewy Body Dementia by Mesenchymal Exosomes/Secretome. International Journal of Molecular Sciences, 2026 May; 27(10): 4483.

Chadwick Prodromos, Andrew Striegel, Gerard Pena, Ruby Del Villar, Rohan Dixit, Angelina Bottalico, and Kenneth Candido. The Intranasal Instillation of the Secretome and Exosomes from Cultured Mesenchymal Stem Cells Significantly Improves the Course of Amyotrophic Lateral Sclerosis with Complete Safety. Posted on ResearchGate, May 2026.

Chadwick Prodromos, Ruby Del Villar, Andrew Striegel, Gerard Pena, Rohan Dixit. A Phase 1/2a Study showing that Intravenous Infusion of an Exosome Solution is Safe and Effective for the Treatment of Neurodegenerative Disorders. Journal of Stem Cells Research Development & Therapy, 2026 February; 12: 118.  

Chadwick Prodromos, Ruby Del Villar, Max Y Jin, Alaa Abd-Elsayed, Kenneth Candido. Exosome-rich Mesenchymal Stem Cell Secretome Improves Strength in Patients with amyotrophic lateral sclerosis, Kennedy disease, congenital myasthenic syndrome and Lewy body dementia. American Journal of Stem Cells, 2025 October; 14(4): 217-229.  

Chadwick Prodromos, Kristian Nenchev, and Leanna Pfeffer. Mesenchymal Stem Cell Treatment Does Not Result in Tumor Formation: A Systematic Review. Journal of Stem Cells Research Development & Therapy, 2025 April; 11: 114.  

Chadwick Prodromos, Mark Hirmiz, Keanne Jabbarzadeh, Ethan Cui, Ruby Del Villar, Arya Asoudegi, and Kenneth Candido. Mesenchymal Stem Cell Injection is Completely Safe, and Effective, for the Treatment of Chronic Back and Neck Pain: A Phase I Clinical Trial. Chronic Pain and Management Journal, 2025 February; 9: 168.

Kenneth Candido, Chadwick Prodromos, and Kristian Nenchev. CT-guided Foramen Ovale Injection of Mesenchymal Stem Cells: First Human Case Report of Trigeminal Neuralgia Relief. Current Stem Cell Research & Therapy, 2024 December; 20(9): 1024-1028.  

Chadwick Prodromos, Mark Hirmiz, and Keanne Jabbarzadeh. Mesenchymal Stem Cell Infusion is Consistently Effective in Improving Autism Behavioral Parameters and EEG Metrics. Journal of Autism Research, 2024 April; 2(1): 1004.

International Cartilage Repair Society (ICRS)
BARCELONA, SPAIN, September 2023
Presentation: Human Pilot Experience Demonstrating the Long-Term Regenerative Properties of Local Immunomodulation Associated with Autologous Stem Cell Therapy Treatments for Osteoarthritis of the Knee and Spine
Moviglia GA, Moviglia-B MT, Bolander J, Piccone S, Updike T, Vaughan W, Mahajan N, Santacoloma E, Grangeat A, Kozima J, Ramirez R, Prodromos C, Atala A, Poheling G

Joshua Sharan, Amir Barmada, Nicolas Band, Eliana Liebman, Chadwick Prodromos. First Report in a Human of Successful Treatment of Asthma with Mesenchymal Stem Cells: A Case Report with Review of Literature. Current Stem Cell Research & Therapy, 2022 Dec; 18(7): 1026-1029.

Chadwick Prodromos, Amir Barmada, Joshua Sharan, Nicolas Band, Tobias Rumschlag, Arwah Yaqub, and Eliana Liebman. Review of the Published Literature Confirms the Safety of Intravenous Infusion of Mesenchymal Stem Cells. Current Stem Cell Research & Therapy, 2022, Sep; 18(6): 779-786.

Chadwick Prodromos, Amir Barmada, Joshua Sharan, and Nicolas Band. Serious Adverse Events Have Not Been Reported with Spinal Intrathecal Injection of Mesenchymal Stem Cells: A Systematic Review. Current Stem Cell Research & Therapy, 2022 Sep; 18(6): 829-833.

Chadwick C. Prodromos, Joshua Sharan, and Amir Barmada. First Human Report of Relief of Lumbar and Cervical Discogenic and Arthritic Back Pain after Epidural and Facet Joint Mesenchymal Stem Cell Injection: A Case Report. Current Stem Cell Research & Therapy, 2022 Aug; 18(7): 1013-1015.

European Society for Sports Traumatology, Knee Surgery and Arthroscopy (ESSKA)
May 2021
Presentation: The Aggregated Data from Normal Saline Placebo Arms of Hyaluronic Acid and Other Knee Injection Studies for OA Can Be Used as a Control Group for Single-Armed Knee Injection Studies”
Chadwick Prodromos, John Lotus, and Susan Finkle

Chadwick Prodromos, and Tobias Rumschlag. Administration of Autologous Mesenchymal Cells for the Treatment of Arthritis. Current Stem Cell Research & Therapy, 2021 Feb; 16(8): 931-938.

Chadwick Prodromos, Susan Finkle, Tobias Rumschlag, and John Lotus. Autologous Mesenchymal Stem Cell Treatment is Consistently Effective for the Treatment of Knee Osteoarthritis: The Results of a Systematic Review of Treatment and Comparison to a Placebo Group. Medicines, 2020 Aug; 7(8): 42.

International Cartilage Repair Society (ICRS)
BERLIN, GERMANY, June 2022
Presentation: PRP Injection of the Arthritic Glenohumeral Joint is Safe, Effective, and Avoids Joint Replacement in Many Patients at 2-8 Year Follow-Up
C. Prodromos, J. Sharan, S. Finkle, N. Band, A. Barmada, A. Schwartz, J. Delapaz

International Cartilage Repair Society (ICRS)
BERLIN, GERMANY, June 2022
Presentation: “PRP Injection Resulted in Joint Replacement Avoidance in 568 OA Knees at 3 - 7 Year Follow-Up, Even Bone on Bone”
C. Prodromos, J. Sharan, S. Finkle, A. Barmada, N. Band, K. Ralston, K. Bruch, K. Phelan, B. Scheuler

International Cartilage Repair Society (ICRS)
BERLIN, GERMANY, June 2022
Presentation: “The Grashey True Shoulder AP X-Ray Accurately Reflects Glenohumeral Joints Space and Predicts PRP Efficacy, The Traditional AP Does Neither:
C. Prodromos, A. Barmada, J. Sharan, S. Finkle, N. Band, J. Delapaz, A. Schwartz, A. Dawes

Chadwick C Prodromos, Susan Finkle, Alexandra Prodromos, Jasmine Li Chen, Aron Schwartz, and Lucas Wathen. Treatment of Rotator Cuff Tears with Platelet Rich Plasma: A Prospective Study with 2-Year Follow-Up. BMC Musculoskeletal Disorders, 2021 May 29; 22(1): 499.

International Federation of Adipose Therapy
MARSEILLES, FRANCE, December 2019
Presentation: “Autologous Biologic Treatment with Fat, Bone Marrow Aspirate, and Platelet Rich Plasma Is an Effective Alternative to Total Knee Arthroplasty for Patients with Moderate Knee Arthrosis”
Chadwick Prodromos and Susan Finkle

Prodromos CC, Finkle S, Dawes A, Dizon A. Intra-Articular Laser Treatment Plus Platelet Rich Plasma (PRP) Significantly Reduces Pain in Many Patients Who Failed Prior PRP Treatment. Medicines 2019; 6(3): 75.  

Guest Editor of an issue of the Open Orthopedics Journal on “Labral Repair Versus Biceps Tenotomy/Tenodesis for the Treatment of Type II SLAP Lesions: Indications and Techniques”. Open Orthop J, 2018, 12: 269-270.
Prodromos CC, Finkle S, Dawes A, Baik JY. Treatment of Type Two Slap Lesion with Anatomic Suture Anchor Repair without Biceps Tenotomy Or Tenodesis. Open Orthop J, 2018, 12: 324-330.

Prodromos CC, Amendola A, Jakob RP. High tibial osteotomy: indications, techniques, and postoperative management. Instr Course Lect, 2015; 64: 555-65.

Prodromos CC. Posterior Mini-incision Hamstring Harvest. Sports Med Arthrosc Rev, March 2010; 18(1): 12-14.

Prodromos CC, Hecker A, Joyce B, Finkle S, Shi K. Elongation of Simulated Whipstitch Post Anterior Cruciate Ligament Reconstruction Tibial Fixation After Cyclic Loading. Knee Surg Sports Traumatol Arthrosc, Aug 2009; 17(8): 914-19.

Prodromos CC, Fu FH, Howell SM, Johnson DH, Lawhorn K. Controversies in Soft-Tissue Anterior Cruciate Ligament Reconstruction: Grafts, Bundles, Tunnels, Fixation, and Harvest. J Am Acad Orthop Surg, July 2008; 16(7):376-84.

Prodromos CC, Han Y, Rogowski J, Joyce B, Shi K. A Meta-Analysis of the Incidence of Anterior Cruciate Ligament Tears As a Function of Gender, Sport, and a Knee Injury-Reduction Regimen. Arthroscopy, Dec 2007; 23(12):1320-1325.

Prodromos CC, Joyce BT, Keller BL, Murphy BJ, Shi K. Magnetic Resonance Imaging Measurement of the Contralateral Normal Meniscus Is a More Accurate Method of Determining Meniscal Allograft Size Than Radiographic Measurement of the Recipient Tibial Plateau. Arthroscopy, Nov 2007; 23(11):1174-1179.

Prodromos C, Joyce B, Shi K. A Meta-Analysis of Stability of Autografts Compared to Allografts After Anterior Cruciate Ligament Reconstruction. Knee Surg Sports Traumatol Arthrosc, July 2007; 5(7):851-6.

Prodromos CC, Joyce BT. Hamstring ACL Reconstruction: Technique, Results, Meta-Analysis, and Posterior Graft Harvest Technique. Techniques in Knee Surgery, June 2006; 5(2): 87-95.

Prodromos CC, Joyce BT, Shi K, Keller BL. A Meta-Analysis of Stability After Anterior Cruciate Ligament Reconstruction as a Function of Hamstring versus Patellar-Tendon Graft and Fixation Type. Arthroscopy, Oct 2005; 21(10):1202el1-9.

Prodromos CC, Han Y.S, Keller BL, Bolyard RJ. Stability Results of Hamstring Anterior Cruciate Ligament Reconstruction at 2- to 8-Year Follow-Up. Arthroscopy, Feb 2005; 21(2): 138-146.

Prodromos CC, Han YS, Keller BL, Bolyard R.J. Posterior Mini-Incision Technique for Hamstring Anterior Cruciate Ligament Reconstruction Graft Harvest. Arthroscopy, Feb 2005; 21(2): 130-137.

Prodromos CC. Low-Profile Cortical Screw Tibial Fixation for Hamstring Anterior Cruciate Ligament Reconstruction: Surgical Technique and Stability Results. Techniques in Orthopaedics, Sept 2005; 20(3): 272-273.

Prodromos CC. Preface: Hamstring Anterior Cruciate Ligament Reconstruction: An Idea Whose Time Has Come. Techniques in Orthopaedics, Sept 2005; 20(3): 191.

Prodromos CC, Joyce B. Five-Strand Hamstring Anterior Cruciate Ligament Reconstruction: Presentation of a New Technique With Better Stability at 7- to 9-Year Follow Up Than 4 Strand. Techniques in Orthopaedics, Sept 2005; 20(3): 192-3.

Prodromos CC. The Posterior Mini-Incision Approach for Hamstring Anterior Cruciate Ligament Graft Harvest. Techniques in Orthopaedics, Sept 2005; 20(3): 200-202.

Prodromos CC, Joyce BT. Tunnel Widening and Hamstring Anterior Cruciate Ligament Reconstruction. Techniques in Orthopaedics, Sept 2005; 20(3): 230-232.

Prodromos CC, Joyce BT. Endobutton Femoral Fixation for Hamstring Anterior Cruciate Ligament Reconstruction: Surgical Technique and Results. Techniques in Orthopaedics, Sept 2005; 20(3): 233-37.

Prodromos CC, Ferry JA, Schiller AL, Zarins B. Histologic Studies of the Glenoid Labrum from Fetal Life to Old Age, J Bone Joint Surg, Oct 1990; 72(A): 1344-1348.

Prodromos CC, Andriacchi TP, Galante JO. A relationship between gait and clinical changes following high tibial osteotomy, J Bone Joint Surg, Oct 1985; 67(A): 1188-1194.

(This paper won both the BERKHEISER AWARD of the Institute of Medicine of Chicago and the RUSH SURGICAL SCIENCES AWARD and was cited as CLASSIC BIBLIOGRPAHY by the American Academy of Orthopedic Surgeons).

Turner DA, Prodromos CC, Petasnick JP, Clark JW. Acute injury of the ligaments of the knee: magnetic resonance evaluation. Radiology; March 1985; 154(3); 717-22.

Dewald RL, Bridwell KH, Prodromos CC, Rodts MF. Reconstructive Spine Surgery as Palliation for Metastatic Malignancies of the Spine. Spine, Jan-Feb 1985; 10(1): 12-16.

Lucas SK, Elmer EB, Flaherty JT, Prodromos CC, Buckley BH, Gott BL, Gardner TJ. Effect of multiple-dose potassium cardioplegia on myocardial ischemia, return of ventricular function, and ultrastructural preservation. J Thorac Cardiovasc Surg, July 1980; 80(1): 102-10.

 

Posterior Mini-Incision Hamstring Graft Harvest Technique for Anterior Cruciate Ligament Reconstruction
-Presented by The American Academy of Orthopaedic Surgeons for presentation 2004 and 2005 annual meetings
-Video Journal of Orthopaedics, #5073, September 2003.